氟磺胺草醚的毒性研究  

Study on the Toxicity of Fomesafen

作　　者：于峰[1] 姚宝玉[1] 王薏[1] 石恩林[1] 杨红光 张静[1] 

机构地区：[1]沈阳化工研究院农药安全评价中心

出　　处：《农药》1997年第7期28-29,共2页Agrochemicals

摘　　要：氟磺胺草醚大鼠经口ＬＤ５０为３１６０毫克／公斤（雄），２８７０毫克／公斤（雌）；小鼠经口ＬＤ５０为４２２０毫克／公斤（雄），４３００毫克／公斤（雌）；大鼠经皮ＬＤ５０＞４６４０毫克／公斤，对家兔眼粘膜、皮肤无明显刺激作用。Ａｍｅｓ小鼠骨髓细胞微核试验和小鼠精子畸形试验均为阴性，无致突变作用。The general and genetic toxicity of fomesafen was studied.Its LD 50 was 3160mg/kg for male rats,2870mg/kg for female rats and 4220～4300mg/kg for mice by oral administration.Its LD 50 was more than 4640mg/kg for rats by dermal administration .There was no obvious irritative to eyes and skin of rabbits.The result of Ames test,micronucleus test and sperm malformation test was negative and no mutagenicity.

关 键 词：氟磺胺草醚 毒性 致突变 除草醚 除草剂 

分 类 号：TQ457.25[化学工程—农药化工]