静注胺碘酮治疗宽大QRS心动过速25例疗效观察  

Cursuve Observation of Amiodarone by Infusion in Treatment of 25 Patients with Tachycardia of Wide-QRS

作　　者：罗景慧[1] 张智慧[1] 

机构地区：[1]哈尔滨医科大学第五临床医学院,黑龙江大庆163316

出　　处：《黑龙江医学》2008年第6期432-433,共2页Heilongjiang Medical Journal

摘　　要：目的观察静脉注射胺碘酮对宽QRS心动过速的疗效及其安全性。方法对25例宽QRS心动过速急诊患者,采用静注胺碘酮,首剂150 mg(3.5 mg/kg)稀释于30 mL生理盐水中,15 min内注入;随后以1.0 mg/min维持静滴,观察30 min无效再给150 mg静注。连续心电监护于用药前及用药后5、10、15、30、120 min测心律、心率和血压及观察其不良反应。结果用药前后对比,心率有显著性差异(P<0.01),1 d内有效率达92%(23/25),血压变化不大(P>0.05),未见明显不良反应。结论静脉注胺碘酮救治宽QRS心动过速,具有快速、安全、效果好的优点。可作为急诊救治宽QRS心动过速的首选药物之一。Objective To observe the efficacy and safety of amiodarone by infusinon to treat tachycardia of wide- QRS. Methods for 25 pauens with tachycardia of wide - QRS, first dose of 150 mg ofamiodarone in 30 minutes, Heart rate, rhytm and blood pressure were observde with continuous electrocardiographic monitoring, meanwhile, toxicities. Results After doses of amiodarone, heart rate dropped significangly （ P 〈 0.01）, with an effective rate of 92% （23/25） within 24 h, but blood pressure not （ P 〉 0.05）, and no toxicity was found. Conclusion amiodarone by infusion was quick, safe to treat patients with tachycardia of wide - QRS, it could be one of first - line drugs.

关 键 词：胺碘酮 心动过速(宽QRS) 救治 疗效 

分 类 号：R540.4[医药卫生—心血管疾病]