壳聚糖支架的水化处理比较研究  

Comparative study on hydration of chitosan scaffolds

作　　者：刘源岗[1] 周长忍[2] 

机构地区：[1]华侨大学材料科学与工程学院,福建省泉州市362021 [2]暨南大学生物材料研究室

出　　处：《中华生物医学工程杂志》2007年第4期213-215,共3页Chinese Journal of Biomedical Engineering

基　　金：国家科技部重大基础研究项目（G199054306）;福建省青年科技人才创新项目（2006F3079）;华侨大学高层次人才科研启动金资助项目（06BS215）

摘　　要：目的比较不同物质对壳聚糖支架进行水化处理后的物理性能及溶剂对酶蛋白分子活性的影响。方法分别用NaOH、氨水，乙醇、丙酮对壳聚糖支架进行水化处理。检测孔隙率、力学强度、支架形貌及酶活性。结果以氨水水化处理后各指标较理想。结论支架材料的后续处理过程宜采用氨水对材料进行水化处理。Objective To campare different materials on hydration of chitosan scaffolds and investigate the influence of abore materials on the activity of enzyme protein. Methods The hydration was performed with NaOH, ammonia, ethanol and acetone. Porosity, elastic modulus, scaffold appearance and enzyme activity were measured respectively. Results Optimal parameters were presented in the hydration of chitosan scaffolds by ammonia. Conclusion Ammonia should be used in the rehydration of chitosan scaffold.

关 键 词：壳聚糖 水化 氨水 

分 类 号：TQ[化学工程]