实验介导椎间盘退变动物模型的研究进展  

Experiment Induced Intervertebral Disc Degeneration Animal Models

作　　者：屈开钛[1] 徐永清[1] 王非[1] 

机构地区：[1]成都军区昆明总医院骨科,云南昆明650032

出　　处：《昆明医学院学报》2008年第B06期219-223,共5页Journal of Kunming Medical College

基　　金：国家自然科学基金资助项目(30400456)

摘　　要：椎间盘退变的动物模型在研究椎间盘退变的研究中有不可替代的作用,通过复习椎间盘退变动物模型的文献对椎间盘退变模型生物力学结构的改变、压力的重新分配或髓核周围纤维环的改变规律进行探讨,为进一步认识椎间盘退变疾病,改进动物模型制作方法,达到提高对椎间盘退变疾病研究水平的目的.An animal model can provide basic science data that support biologic plausibility. Studies are classified as either experimentally induced or spontaneous. Where experiment induced models are subdivided mechanical or structural. Spontaneous models include those animals that naturally develop degenerative disc disease. To study these current animal models are important and useful for the improvements of building up new animal models and improve the study level of research the intervertebral disc degeneration disease.

关 键 词：椎间盘退变 动物模型 软骨终板 

分 类 号：R453.9[医药卫生—治疗学]