复方蛤青片质量标准的改进  

Improvement of Quality Standard for Fufang Haqing Tablets

作　　者：方道硕[1] 贾晶[2] 黄春燕[2] 张小琳[2] 

机构地区：[1]成都铁路中心医院,成都市610081 [2]成都中医药大学,成都市610072

出　　处：《中国药房》2008年第18期1401-1403,共3页China Pharmacy

摘　　要：目的：改进复方蛤青片的质量标准。方法采用薄层色谱法对方中前胡、南五味子进行定性鉴别；采用高效液相色谱-蒸发光散射检测法测定黄芪甲苷的含量。结果：定性鉴别斑点清晰，分离度好；黄芪甲苷进样量在1．4472～16．0800μg范围内与峰面积积分值呈良好的线性关系（r=0．9996）；平均加样回收率为99．68％，RSD=1．16％（n=6）。结论：本方法进一步完善了复方蛤青片的质量标准。OBJECTIVE： To improve the quality standard for Fufang haqing tablets. METHODS： Radix Peucedani, Fructus Schisandrae Sphenantherae in the recipe were identified by TLC, and the content of Astragaloside IV was determined by HPLC- ELSD method.RESULTS： Radix Peucedani and Fructus Schisandrae Sphenantherae showed clear TLC spots and good resolution. Astragaloside Ⅳ showed a good linear relationship within the range of 1.447 2-16.080 0 μg （r = 0.999 6） . The average recovery was 99.68% with the RSD at 1.16% （n = 6）. CONCLUSION： The established method further improved the quality standard of Fufang haqing tablets.

关 键 词：复方蛤青片 高效液相色谱-蒸发光散射检测法 薄层色谱法 质量标准 

分 类 号：R283.64[医药卫生—中药学] R927.1[医药卫生—中医学]