十齿花化学成分研究  

Chemical constituents of Dipentodon sinicus

作　　者：叶冠[1] 彭华[2] 范明松[1] 黄成钢[1] 

机构地区：[1]中国科学院上海生命科学研究院上海药物研究所,上海201203 [2]中国科学院昆明植物研究所,云南昆明650204

出　　处：《中草药》2008年第6期808-810,共3页Chinese Traditional and Herbal Drugs

摘　　要：目的研究十齿花的化学成分。方法采用硅胶柱色谱及Sephadex LH-20等色谱技术分离纯化,根据理化性质及波谱数据鉴定结构。结果从十齿花的乙醇提取物中共分离得到9个化合物,分别为正三十醇(Ⅰ)、β-谷甾醇(Ⅱ)、邻苯二酚(Ⅲ)、对苯二酚(Ⅳ)、松柏醛(Ⅴ)、香草酸(Ⅵ)、麦角甾醇过氧化物(Ⅶ)、β-谷甾醇-3-O-β-D-葡萄糖-3′-O-三十三烷酸酯(Ⅷ)、胡萝卜苷(Ⅸ)。结论9个化合物均为首次从该植物中分得,其中化合物Ⅷ为新化合物,命名为十齿花素。Objective To study the chemical constituents from Dipentodon sinicus. Methods Isolation and purification were carried out on silica gel column and Sephadex LH-20, the structures were elucidated on the basis of chemical evidences and spectral analysis. Results Nine compounds were isolated and their structures were identified as n-l-triacontanol （ I ）, β-sitosterol （ Ⅱ ）, pyrocatechol （ Ⅲ ）, p-dihydroxyl benzene （ IV ）, coniferyl aldehyde （ V ）, vanillic acid （ Ⅵ ）, ergosterol peroxide （Ⅶ）, 13-sitosterol-3-O-β-D-glucosides-β-O-tritriacontanate （Ⅷ）, and daucosterol （IX）. Conclusion All the nine compounds are isolated from the title plant for the first time, among them, compound -Ⅷ is a new compound named as dipentosinin.

关 键 词：十齿花 卫矛科 十齿花素 

分 类 号：R284.1[医药卫生—中药学]