瑞丽市海洛因成瘾者美沙酮维持治疗效果评价  

Effect assessment of methadone maintenance treatment among heroin addicts in Ruili city

作　　者：段一娟[1] 尹正留 郗承惠 李忠诚[1] 高云[1] 杨光文[1] 段娟[1] 杨鲁[1] 吴华珍[1] 杨盈波 姚红云[1] 邱香归 关振园[2] 斗智[2] 

机构地区：[1]瑞丽市疾病预防控制中心,云南瑞丽678600 [2]中国疾病预防控制中心性病艾滋病预防控制中心,北京100050

出　　处：《中国艾滋病性病》2008年第3期240-242,共3页Chinese Journal of Aids & STD

摘　　要：目的评价瑞丽市对海洛因成瘾者进行美沙酮社区维持治疗(MMT)一年的治疗效果。方法对美沙酮门诊的99名海洛因成瘾者的基线数据和治疗一年后的随访数据进行比较。结果一共收集了99名受治者的基线和治疗一年后的随访数据。基线与随访比较,入组前66名受治者HIV抗体检测阴性,经过一年的MMT后,此66名受治者HIV抗体仍然阴性;受治者的尿检阳性率从入组前的100%下降到治疗后的23.23%,承认注射吸毒、注射吸毒次数、共用针具吸毒的比例明显减少,安全套坚持使用率从25%提高到31.4%;通过MMT恢复了家庭和社会功能。结论通过MMT一年后,在减少危险行为,减少与毒品相关的违法犯罪,恢复与提高个人、家庭与社会功能方面取得了比较好的效果,对预防控制艾滋病通过注射吸毒与性行为传播起到了积极的作用。Objective To examine the effect of the community-based methadone maintenance treatment （MMT）among heroin addicts for a period of 12 months. Methods Baseline survey and follow-up investigation after 12 month treatment were conducted in 99 heroin addicts receiving MMT, and the baseline and follow up data were compared. Results The HIV antibody detection showed that 66 HIV negative individuals at entry remained negative after 12 month treatment. The positive rate of urine test dropped from 100 % at baseline to 23.3 % after the treatment. The proportion of the injection-related risk behaviors, such as drug injection, frequency of injection, and syringe and needle sharing, was also reduced significantly. The rate of consistent condom use increased from 25 % to 31.4 % in the past 12 months. MMT in general contributed to the restoration of family and social function. Conclusion As a result of 12 month treatment MMT has achieved encouraging effect in terms of reducing risk behaviors and drug related crimes and improving or restoring individual, family and social functions, and so has made positive contribution to the prevention of HIV/AIDS spread via drug use and sex.

关 键 词：海洛因成瘾者 社区美沙酮维持治疗门诊 效果 

分 类 号：R966[医药卫生—药理学]