思密达治疗婴幼儿急性腹泻的探讨  

STUDY ON SMECTA THERAPY FOR ACUTE DIARRHEA IN INFANT

作　　者：宗珊[1] 曹玉明[1] 屈勇 刘宁[1] 

机构地区：[1]天津市第三中心医院儿科

出　　处：《天津医科大学学报》1997年第4期60-63,共4页Journal of Tianjin Medical University

摘　　要：为了探讨思密达对婴幼儿急性腹泻的治疗效果，我们将年龄在３岁以下，粪便呈水样便或蛋花汤样便，病程在５天以内符合病毒性腹泻的４５例急性腹泻患儿，随机抽样２０例取新鲜便作快速轮状病毒抗原检测，轮状病毒感染率为７５％。将病例随机分为三组：２０例为思密达治疗组；１０例为乳酸菌素片对照组；１５例为思密达联合抗生素对照组。治疗后三组结果：思密达治疗组和思密达联合抗生素对照组的总有效率分别为９５％、９３．５％，与乳酸菌素片组对照有显著差异（Ｐ＜０．０５）。尤其在平均退热天数和止泻天数方面都显著优于乳酸菌素片组（Ｐ≤０．０１）。思密达组与思密达联合抗生素组比较疗效无差异。This study was undertaken to evaluate therapeutic effect of Smecta on acute diarrhea in infantTotally 45 children(under age of 3 years)with acute virus diarrhea and the course within 5 days were involved in this study Rotavirus specific antigen was deteted repidly by using of ELISA in 20 patiens75% of positive rate was observed  The patients were divided into 3 groups,group A cases (n=20) were treated with Smecta ;group B cases (n=10) were treated with lactein tablet; group C cases(n=15) were treated with Smecta and antibiotics as control groupThe results of the study showed that the effective rate of group A and group B was 95% and 935% respectively,and there was significant difference with group B(P<005)Especially in the time of abating fever and antidiarrhea ,which was obviously superior to group B (P≤001)  No obvious difference was found between group A and group C

关 键 词：婴幼儿腹泻 思密达 急性 治疗 

分 类 号：R512.505[医药卫生—内科学] R975[医药卫生—临床医学]