冬凌草化学成分研究  

Study on Chemical Constituents of Rabdosia rubescens (Hemsl.) Hara Herb

作　　者：卢海英[1] 梁敬钰[1] 陈荣[1] 喻娟[1] 

机构地区：[1]中国药科大学天然药物化学教研室,江苏南京210009

出　　处：《林产化学与工业》2008年第3期7-12,共6页Chemistry and Industry of Forest Products

摘　　要：对唇形科香茶菜属植物冬凌草进行化学成分研究,从其中分得7个化合物,经理化和波谱方法分别鉴定为:双冬凌草丁素(Ⅰ),(10Z,14Z)-9,16-二羰基-10,12,14-三烯-十八碳酸(Ⅱ),2′-乙酰氨基-3′-苯基丙基2-苯甲酰氨基-3-苯基丙酸酯(Ⅲ),α-香树脂醇(Ⅳ),β-香树脂醇(Ⅴ),2β-羟基齐墩酸(Ⅵ),2α-羟基乌索酸(Ⅶ)。其中化合物Ⅰ为一个新的对映-贝壳杉烷二萜二聚体,Ⅱ为新的高度不饱和脂肪酸,化合物Ⅲ和Ⅵ为首次从该属植物中得到,化合物Ⅴ为首次从该植物中得到。The chemical constituents of Rabdosia rubescens （ Hems1. ） Hara herb were studied. Seven compounds were isolated and their structures were elucidated by various spectroscopic methods as bisrubescensin D （ I ）, （10Z, 14Z）-9, 16-dioxo- octadec-10,12,14-trienoic acid （ Ⅱ ）, 2＇-acctamido-3＇-phenyl propyl 2-benzamido-3-phenyl propionate （ Ⅲ ）, α-amyrin （ Ⅳ ）, β-amyrin （ V ） , olean-12-en-2]3,3]3-diol-28-oic acid （augustic acid, VI ） , 2α-hydroursolic acid （Ⅶ）. Compound I is a novel asymmetric ent-kauranoid dimmer, compound Ⅱ is a new unsaturated fatty acid, compounds Ⅲ and VI were obtained from this genus of plants for the first time, and compound V was obtained from this plant for the first time.

关 键 词：冬凌草 对映-贝壳杉烷二萜二聚体 脂肪酸 生物碱 三萜 

分 类 号：TQ91[化学工程]