3,5-二羟基查尔酮的合成  

Synthesis of 3,5-dihydroxy chalcone*

作　　者：石秀梅[1] 邓士英[1] 邹桂华[1] 岳司佳[1] 

机构地区：[1]牡丹江医学院药学系,黑龙江牡丹江157011

出　　处：《化学工程师》2008年第6期8-9,共2页Chemical Engineer

基　　金：黑龙江省卫生厅科研课题(2003-152);黑龙江省教育科学规划课题(738)

摘　　要：探索黄酮类化合物的合成方法。采用一种新方法,通过酰基化、Fries重排、醇醛缩合反应,合成了3,5-二羟基查尔酮,获得了满意的收率(80%)。该方法具有反应时间短、操作简便、收率高等优点。The synthetic methods of flavonoids were studied. Synthesis of 3,5 -dihydroxy chalcone was accomplished by acylation, Fries rearrange reaction and aldol condensation. 3,5 - Dihydroxy chalcone was synthesize and a good yield（80% ） was obtained. This method is charactered by the reaction time being short,the operation process being simple and the yield being good.

关 键 词：间苯二酚 3 5-二羟基查尔酮 合成 

分 类 号：TQ243[化学工程—有机化工]