亚急性三氯丙烷中毒10例临床分析  

Clinical analysis on 10 cases of subacute 1,2,3-trichloropropane poisoning

作　　者：孙道远[1] 张巡淼[1] 

机构地区：[1]上海市肺科医院上海市职业病医院,上海200433

出　　处：《中国工业医学杂志》2008年第3期154-156,共3页Chinese Journal of Industrial Medicine

摘　　要：目的通过对亚急性三氯丙烷中毒病例分析,了解其临床特点。方法通过现场职业卫生学调查和收集10例亚急性三氯丙烷中毒病例临床资料包括症状、体征、实验室检查结果,进行综合分析。结果亚急性三氯丙烷中毒患者均以肝脏损害为主要表现,其中乏力、食欲下降最为突出,并伴有多种肝内酶升高,2例患者入院后出现体温升高及直接胆红素持续增高。结论亚急性三氯丙烷中毒的临床特点主要是肝脏损害,病情严重程度除与接触情况有关外,还应考虑影响其表现的其他因素,尤其个体原有肝脏基础疾病应引起重视。Objective To study the clinical characteristics of subacute 1,2,3-trichloropropane poisoning through the clinical analysis on the cases. Methods The clinical records of 10 subacute 1 ,2,3-trichloropropane poisoning cases were collected, after comprehensive analysis on the symptoms, physical signs, laboratory indices and the occupational investigation data, then a reliable conclusion was obtained. Results The most outstanding clinical characteristics of occupational subacute 1,2,3-trichloro propane poisoning are the hepatic injury （risen hepatic enzymes and bilirubin）, fatigue and loss of appetite. Conclusion It is suggested the main clinical feature of subacute 1,2,3-trichloropropane poisoning is hepatic injury, which might be affected by other factors, especially the pre-existing hepatic disease.

关 键 词：1 2 3-三氯丙烷 亚急性中毒 临床分析 

分 类 号：O623.21[理学—有机化学] R135.1[理学—化学]