持续颅内压监测下观察甘露醇不同输注速度的降压效果  

Observation of Pressure-lowering Effect of Mannitol in Sustained Intracranial Pressure Monitoring

作　　者：周秀红[1] 黄水英[1] 林御贤[1] 刘利兰[1] 

机构地区：[1]深圳市龙岗中心医院神经外科,广东深圳518116

出　　处：《护理学报》2008年第6期1-2,共2页Journal of Nursing（China）

基　　金：深圳市卫生科技计划立项项目(200404191)

摘　　要：目的了解不同速度静脉滴注甘露醇降压效果及作用维持时间。方法将需要定时使用甘露醇的患者随机分为3组,观察1组:10min内输完,观察2组:11～20min输完,观察3组:21～30min输完,分别在输注甘露醇前和输完甘露醇时、输完甘露醇后30min、输完甘露醇后6h记录颅内压I(CP)值,观察不同速度输注甘露醇患者ICP的变化。结果3组输完甘露醇后30min内患者的ICP都有下降,以观察1组变化的幅度最大。6h后患者ICP恢复至使用甘露醇前的水平。结论使用甘露醇降压时,输注速度越快,其降压效果越好,建议甘露醇使用的间隔时间以6h为宜。Objective To explore the intracranial pressure （ICP） lowering effects of mannitol injected at different speeds and the effect duration. Methods The patients needing mannital injection were divided into 3 groups at random： the injection for Group A was completed in 10 minutes, Group B, 11-20 minutes, and Group C, 21-30 minutes. ICP values before and during the injection and those 30 minutes and 6 hours after the injection were recorded; changes in the IPC values of the 3 groups were compared. Results 30 minutes after the completion of the injection of mannitoi, the ICP of the patients of all the 3 groups were decreased, with that of Group A being decreased most greatly. And 6 hours after the completion, the level of ICP returned to that before the injection of mannitol. Conclusion The greater the mannitol injection speed, the better the effect of pressure lowering. It was advised that interval between mannitol injections be 6 hours.

关 键 词：持续颅内压监测 甘露醇 输液速度 降压效果 

分 类 号：R473.6[医药卫生—护理学]