埃索美拉唑联合莫沙比利治疗反流性食管炎的临床研究  

作　　者：杨名诗[1] 余权珍[1] 

机构地区：[1]广东医学院附属医院消化内科,524001

出　　处：《中国社区医师（医学专业）》2008年第13期18-18,共1页

摘　　要：目的:研究埃索美拉唑联合莫沙比利治疗反流性食管炎的效果。方法:联合组48例采用埃索美拉唑20mg,每日早晨空腹服用,莫沙比利5mg,每日3次,餐前半小时服用;对照组46例单用埃索美拉唑20mg,每日早晨空腹服用。观察对比两组的疗效及总有效率。结果:联合组显效31例,有效13例,总有效率91.7%;对照组显效17例,有效15例,总有效率69.6%,两组比较差异有统学意义(P<0.05)。结论:埃索美拉唑联合莫沙比利治疗反流性食管炎,效果优于单用埃索美拉唑。Objectiv：To investigate the efficacy of Escomeprazole combined with Mosapride in the treatment of reflux esophagitis. Method ： Patients of experimental group （ n = 48） took Escomeprazole 20mg in the morning on an empty stomach once a day and Mosapride 5mg three times a day before eating;patients of control group （ n = 46 ）, the patients only took Esomeprazote 20mg in the morning on an empty stomach once a day. The efficacy and total effective rate between were compared. Resuhs：A total of 31 cases had significant effect and 13 cases had valid effect in experimental group, the total effective rate was 91.7% ;A total of 17 cases had significant effect and 15 cases had valid effect in control group, the total effective rate was 69.6% ;the difference was significant between two groups （ P 〈 0.05 ）. Conclusion ： Combination of Escomeprazole and Mosapride is effective in the treatment of reflux esophagitis.

关 键 词：埃索美拉唑 莫沙比利 食管炎 临床研究 

分 类 号：R975[医药卫生—药品] R571[医药卫生—药学]