十大功劳对小鼠血清超氧化物歧化酶活性及丙二醛含量的影响  

Effect of Mahonia on the SOD Activity and MDA Content in Serum of Mice

作　　者：余庆皋[1] 严丹华[1] 刘捷频[1] 熊志青[1] 

机构地区：[1]湘潭职业技术学院,湖南湘潭411102

出　　处：《时珍国医国药》2008年第6期1332-1333,共2页Lishizhen Medicine and Materia Medica Research

基　　金：湖南省湘潭市2007年科技项目立项课题(No.JZ200717)

摘　　要：目的研究中药十大功劳在小鼠体内的抗氧化作用。方法用不同浓度十大功劳水煎液喂养小鼠4周,眼眶取血,用超氧化物歧化酶(SOD)试剂盒和丙二醛(MDA)试剂盒测定小鼠血清SOD活性和MDA含量。结果与对照组比较,喂药组小鼠血清SOD活性升高,MDA含量降低。结论十大功劳在小鼠体内具有抗氧化作用,能升高血清SOD的活性,降低血清过氧化脂质产物MDA的含量。Objective：To study the antioxidative effect of mahonia. Methods： The mice were fed with Mahonia water decoction in different concentrations for four weeks ,the blood samples from the orbit were collected and the SOD（ Superoxide Dismatase） activity and M DA（Malondialdehyde） content serum of mice were measured by using SOD kit ＆ M DA kit. Results：Compared with the control group ,the SOD activity in serum in the experiment groups was inereased, the MDA content was decreased, Conclusion： Mahonia has antioxidative effect by inereasing the SOD activity of serum and lowering the content of serum lipid peroxidation product MDA.

关 键 词：十大功劳 小鼠 超氧化物歧化酶 丙二醛 

分 类 号：R285.5[医药卫生—中药学]