手性氯化利巴韦林合铜(Ⅱ)的合成、结构和光谱性质  

Synthesis,Structure and Spectral Characterization of Chiral Ribavirin Copper Chloride Complex

作　　者：戈根武[1] 杨瑞卿[2] 谢永荣[1] 

机构地区：[1]赣南师范学院化学与生命科学学院 [2]赣南师范学院校医院,江西赣州341000

出　　处：《赣南师范学院学报》2008年第3期92-94,共3页Journal of Gannan Teachers' College(Social Science(2))

基　　金：江西省自然科学基金项目(0620007);江西省教育厅科学技术项目(20060237)

摘　　要：利巴韦林与氯化铜反应形成了蓝色柱状氯化利巴韦林合铜(II)配合物.本文研究了其晶体结构,红外和紫外光谱,差热-热重和溶解性等性质.表明该配合物易溶于水、微溶于甲醇和乙醇,有改进其药效的较大潜力.The complexation between ribavirin and copper dichloride produced a blue strip crystal. The single-crystal X-ray diffraction analysis was taken to determine the crystal structure of the complex. The characteristics of the complex were studied in means of IR spectra, UV spectra and TG-DTA analysis. The crystal complex was soluble in water but slightly soluble in methanol and ethanol that could be latent medicine.

关 键 词：合成 结构 光谱性质 利巴韦林 铜配合物 

分 类 号：O627.12[理学—有机化学]