我国部分地区鸡致病性大肠杆菌的耐药性检测与分析  

Resistance detection and analysis of pathogenic Escherichia coli to antimicrobials in chicken farms

作　　者：刘聚祥[1] 李宏娟[1] 李占雷[1] 陈立功[1] 高振同 李政萍[1] 董世山[1] 

机构地区：[1]河北农业大学,河北保定071001 [2]河北省兽药监察所,河北石家庄050051

出　　处：《河北农业大学学报》2007年第5期94-98,共5页Journal of Hebei Agricultural University

基　　金：河北省自然科学基金资助项目(C2004000329)

摘　　要：用氟苯尼考、氧氟沙星等12种抗菌药物对从东北、河北、山东、华东等地部分鸡场分离的21株鸡致病性大肠杆菌进行药物敏感性测定。结果表明,分离菌对阿莫西林的耐药性最高,为100%,余下依次为四环素95.24%、诺氟沙星85.71%、多西环素66.67%、氧氟沙星61.9%、硫酸链霉素61.9%、环丙沙星57.14%、氟苯尼考57.14%、红霉素38.1%、硫酸庆大霉素23.89%、新霉素19.05%、阿米卡星19.05%。分离菌表现出多重耐药性,7重耐药菌株最多,达6株(28.57%),4重、5重、6重耐药各3株(14.29%),8重、11重耐药的各2株(9.52%),9重、10重耐药的各1株(4.76%)。The resistances of 21 strains of avian pathogenic E. coli isolated from some chicken farms in Northeast China Provinces, Hebei, Shandong and East China regions to 12 antimicrobials were examined. The resistance rates to Amoxicillin, Tetracycline, Norfloxacin, Doxycycline, Ofloxacin, Streptomycin Sulfate, Ciprofloxacin, Florfenicol, Erythromycin, Gentamicin Sulfate, Neomycin, Amikacin were 100%, 95.24%, 85.71%, 66.67%, 61.9%, 61.9%, 57.14%, 57.14%, 38.1%, 23.89%, 19.05% and 19.05%, respectively. All of the isolates showed multiple - resistances The resistance spectrum of the isolates varied from 4 to 11 kinds of the above antimicrobials. Seven resistances were 6 strains （28.57%）; four, five and six resistances were 3 strains （14.29%）, eight and eleven resistances were 2 strains （9.52%）, nine and ten resistances were 1 strain （4.76 % ）, respectively.

关 键 词：鸡 致病性大肠杆菌 抗菌药物 耐药性 

分 类 号：S858.31[农业科学—临床兽医学]