肾小管上皮细胞转分化与肾小管间质纤维化  

Epithelial-mesenchymal transition and its implications for fibrosis

作　　者：姚俊霞[1] 吴人亮[2] 

机构地区：[1]郧阳医学院,湖北十堰442000 [2]华中科技大学同济医学院,湖北武汉430000

出　　处：《中国现代医学杂志》2008年第11期1561-1564,共4页China Journal of Modern Medicine

摘　　要：肾小管上皮细胞转分化在肾间质纤维化发生中起到重要作用,其转化条件和机制已成为当今学者研究的热点。该文就肾小管上皮细胞转分化过程及可能的发生机制进行综述。Emerging evidence suggests that tubular epithelial-mesenchymal transition （EMT） is an important factor in renal tubulointerstitial fibrosis. This review describes the recent findings in the context of the tubular epithelial-mesenchymal transition process and discusses the possible mechanisms involved.

关 键 词：肾小管 上皮细胞 转分化 纤维化 

分 类 号：R692[医药卫生—泌尿科学]