缺血性心肌病血清脑钠肽的临床研究  

Clinical research of serum brain natriuretic peptide levels in patients with chronic ischemic cardiomyopathy

作　　者：王友敏 王绍欣[2] 李转珍[2] 李晓玲[2] 汪砚雨[2] 李春燕[2] 

机构地区：[1]河南省洛阳电力医院心内科,河南洛阳471003 [2]河南科技大学第一附属医院心内科,河南洛阳471003

出　　处：《中国现代医学杂志》2008年第11期1578-1580,1584,共4页China Journal of Modern Medicine

摘　　要：目的探讨缺血性心肌病患者血清脑钠肽(brain natriuretic peptide,BNP)的变化及临床意义。方法测定缺血性心肌病患者40例及正常人20例空腹血清BNP、心率、左室舒张末内径(LVDD)、左室射血分数(LVEF)等指标。结果缺血性心肌病患者血清BNP、LVEDD、心率均显著高于对照组(P<0.01)。LVEF显著低于对照组(P<0.01)。结论血清BNP水平对缺血性心肌病患者的诊断、治疗及预后判断具有重要临床意义。[Objective] To investigate the clinical research of serum brain natriuretic peptide （BNP） levels in patients with ischemic cardiomyopathy. [Methods] serum brain natriuretic peptide levels, LVDD and LVEF were measured in 40 patients with ischemic cardiomyopathy and 20 healthy subjects served as control group. [Results] ischemic cardiomyopathy patients had higher serum BNP, LVDD and heart rate compared with normal subjects（P 〈 0.01）, the means of LVEF was reverse （P 〈0.01）. [Conclusions] The level of serum BNP may play an important role in the diagnosis and prognosis of patients with ischemic cardiomyopathy.

关 键 词：脑钠肽 缺血性心肌病 诊断 预后 

分 类 号：R542.2[医药卫生—心血管疾病]