EST预防急性胆源性胰腺炎复发的临床研究  

Clinical implications of preventing the recurrence of the acute gallstone pancreatitis by using the EST technology

作　　者：周鸣清[1] 陈欣然[1] 陆仁达[1] 

机构地区：[1]上海市闸北区中心医院肝胆胰外科,200070

出　　处：《中国医药指南（学术版）》2008年第2期131-132,共2页Guide of China Medicine

摘　　要：目的:探讨内镜下乳头括约肌切开(EST)对预防急性胆源性胰腺炎(ABP)复发的临床价值。方法:将临床治愈的296例ABP患者分为EST治疗组(n=119)和非EST对照组(n=177)。将两组患者进一步分为胆囊切除组和非胆囊切除组。随访所有ABP患者,比较二组复发率有无显著差异。结果:两组ABP患者,平均随访时间32±14月;15例失访,随访率94.9%。EST治疗组(11/113)的复发率明显低于非EST治疗组(75/168),其差异有显著性,P<O.01;而胆囊切除虽然能降低ABP的复发率,但其差异无显著性P>0.05。结论应用EST技术治疗ABP,可预防ABP的再次发作。Objective Explore the clinical value of preventing the recurrence of the acute biliary pancreatitis, （ABP） by using the endoscopic sphincterotomy （EST）. Methods The 296 cured patients with ABP were divided into EST treatment group （n=119） and non-EST control group （n=177）. Each group was further broken down into cholecystectomy group and non-cholecystectomy group. Follow-up visits were paid to all patients with ABP and comparisons were made to see whether the recurrence rate of the cases between the two groups had any significant importance. Results All patients with ABP. Follow up of average 32±14months. Visits in 281 out of the remaining 296 cases （94.9%）. The recurrence rate for the cases in the ABP and EST groups （11/113） were explicitly lower than that for the patients in the non-EST control （75/168）, with their difference having significant importance （P〈0.01）. When further comparisons were made, their difference showed no significant importance （P〉0.05） although cholecystectomy could reduce the recurrence rate of the patients with ABP Conclusion The treatment of patients with ABP by using EST can prevent the recurrence of patients with the ABP.

关 键 词：急性胆源性胰腺炎 ERCP EST 

分 类 号：R657.51[医药卫生—外科学]