善得定在术后早期炎症性肠梗阻治疗中的作用  

作　　者：聂剑[1] 黎小明[1] 黎小燕[1] 

机构地区：[1]广东省肇庆市第一人民医院,526021

出　　处：《中国医药指南（学术版）》2008年第5期12-14,共3页Guide of China Medicine

摘　　要：目的探讨善得定在术后早期炎症性肠梗阻治疗中的作用。方法41例术后早期炎症性肠梗阻患者随机分为对照组(19例)和善得定组(22例),对照组采用常规禁食、胃肠减压、补液、维持水电解质和酸碱平衡、抗感染等传统方法治疗;治疗组在对照组采取的措施基础上,再加用善得定(奥曲肽)0.1mg,每8h一次,连用3～10d。结果两组的一般资料在性别、年龄、手术方式及术中腹腔粘连或渗液方面的差异无统计学意义。两组相比,善得定组胃肠减压引流量减少,临床症状缓解迅速,肛门排气时间提前,平均住院时间缩短,差异均有显著性。结论善得定是治疗术后早期炎症性肠梗阻的一种有效药物。Objective To investigate the effect of octreotide in the treatment of early postoperative inflammatory intestinal obstruction. Methods 41 cases of early postoperative inflammatory intestinal obstruction were divided into two group： control group （19 cases） and sandostatin group（22 cases）. The patients of control group were treated with fasting, gastrointestinal decompression, clys%, maintaining electrolyte and acid-base balance, anti-infective; The patients of octreotide group were treated with all the same treatment of control group and sandostatin （octreotide）0. img H qSh for 3-10 days. Results There were no signficant dfferences in gender,age operating method and abdominal adhesions between two groups. In sandostatin group, the quantity of gastrointestinal decompression decreased obviously, clinical symptoms relieved more quickly, the average anal exhaust time advanced obviously, the average hospitalization time also shortened, there were signficant differences compared with control group respectively. Conclusion Sandostatin is an effective drug in the treatment of early postoperative inflammatory intestinal obstruction.

关 键 词：善得定 术后早期炎症性肠梗阻 

分 类 号：R97[医药卫生—药品]