消痛合剂对子宫内膜异位症大鼠血浆PGE2、6-keto-PGF1α水平的影响  

作　　者：赵良倩[1] 王荣幸[1] 

机构地区：[1]山东省临沂市中医医院,276002

出　　处：《中国医药指南（学术版）》2008年第7期4-6,共3页Guide of China Medicine

摘　　要：目的观察消痛合剂对子宫内膜异位症大鼠血浆PGE_2,6-keto-PGF1水平的影响。方法手术建立SD大鼠子宫内膜异位症模型,予消痛合剂治疗,并与西药米非司酮对照。结果和结论消痛合剂能调节子宫内膜异位症大鼠血浆PGE_2,6-keto-PGF1α水平,与米非司酮比较无显著差异,提示调节子宫内膜异位症大鼠血浆PGE_2、6-keto-PGF1α水平是消痛合剂治疗子宫内膜异位症的机制之一。Objective To investigate the influence of Xiaotongheji on Plasma PGE2, 6-keto-PGF1 α Level in Endometriosis Rats Method A SD rat model of endometriosis was made by operation. The rats were treated by Xiaotongheji or with Western medicine Mifepristone as a control. Results and Conclusion Xiaotongheji could adjust plasma PGE2, 6-keto-PGF1 α level in endometriosis rats, and its effect was not significally different from that of Mifepristone. It is suggested that adjust plasma PGE2, 6-keto PGF1 α level is one of the mechanisms by which Xiaotongheji treats endometriosis.

关 键 词：子宫内膜异位症 血浆PGE2 6-KETO-PGF1Α 消痛合剂 米非司酮 大鼠 

分 类 号：R711.71[医药卫生—妇产科学]