腰椎间盘突出的自身免疫反应及其法医学意义  

Autoimmune response of lumbar disc herniation and its significance in forensic medicine

作　　者：杨帆[1] 刘兴本[2] 李冯锐[1] 汤鹏[1] 

机构地区：[1]中国医科大学法医学院临床法医学教研室 [2]包头医学院法医学系,内蒙古包头014010

出　　处：《中国法医学杂志》2008年第3期181-183,共3页Chinese Journal of Forensic Medicine

摘　　要：损伤时间推定与伤、病鉴别,一直是法医学领域研究的重要课题。腰椎间盘突出是一种以人的生理退行性变为基础的改变,为了寻找准确推断其发生时间的方法,本文综述了腰椎间盘突出后机体细胞免疫、体液免疫反应与损伤时间的关系。认为进一步研究突出髓核组织局部与外周循环中IgG、IgM表达的特征性变化,有望成为推定损伤时间的方法之一。Dating of injury and the discrimination in trauma and disease is always an important hot topic in the field of forensic medicine. Lumbar disc herniation is a kind of physiological degeneration. To seek a method for deducing the occurrence time of traumatic LDH exactly, this article reviewed the correlation between humoral, celllur immunity and the occurrence time of LDH. It is suggested that some characteristic changes of the expression of IgG, IgM, macrophages may be a helpful method for the occurrence time deduction of traumatic LDH.

关 键 词：法医临床学 腰椎间盘突出 损伤时间推断 自身免疫反应 

分 类 号：D919[医药卫生—法医学]