Ultrahigh resolution optical coherence tomography with femtosecond Ti:sapphire laser and photonic crystal fiber  

作　　者：XUE Ping James G FUJIMOTO 

机构地区：[1]Department of Physics, Laboratory of Atomic and Molecular Nanosciences of Ministry of Education, Tsinghua University, Beijing 100084, China [2]Department of Electrical Engineering and Computer Science, Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139-4307, USA

出　　处：《Chinese Science Bulletin》2008年第13期1963-1966,共4页

基　　金：the National Basic Research Program of China (Grant No.001CB510307);Hi-tech Research and Development Program of China (Grant No.2006AA02Z472);National Natural Science Foundation of China (Grant Nos.90508001,10574081);the Ministry of Education of China (Grant No.306020)

摘　　要：Optical coherence tomography (OCT) with ultrahigh axial resolution was achieved by the super-contin-uum generated by coupling femtosecond pulses from a commercial Ti:sapphire laser into an air-silica microstructure fiber. The visible spectrum of the super-continuum from 450 to 700 nm centered at 540 nm can be generated. A free-space axial OCT resolution of 0.64 μm was achieved. The sensitivity of OCT system was 108 dB with incident light power 3 mW at sample,only 7dB below the theoretical limit. Subcellular OCT imaging was also demonstrated,showing great potential for biomedical application.Optical coherence tomography （OCT） with ultrahigh axial resolution was achieved by the super-continuum generated by coupling femtosecond pulses from a commercial Ti：sapphire laser into an air-silica microstructure fiber. The visible spectrum of the super-continuum from 450 to 700 nm centered at 540 nm can be generated. A free-space axial OCT resolution of 0.64 pm was achieved. The sensitivity of OCT system was 108 dB with incident light power 3 mW at sample, only 7dB below the theoretical limit. Subcellular OCT imaging was also demonstrated, showing great potential for biomedical application.

关 键 词：X线摄影 连续介质 晶体纤维 蓝宝石激光 

分 类 号：O72[理学—晶体学]