超声法提取金鸡纳生物碱的工艺  

Study on ultrasonic wave extraction of alkaloid from Cinchona

作　　者：蒲含林[1] 郑元升[1] 麻建军[1] 

机构地区：[1]暨南大学生物工程研究所,广东广州510632

出　　处：《暨南大学学报（自然科学与医学版）》2008年第3期329-330,共2页Journal of Jinan University(Natural Science & Medicine Edition)

摘　　要：研究金鸡纳总生物碱的超声提取工艺.采用L9(34)正交设计通过正交试验得出了超声提取的最佳工艺条件.超声提取的影响因素顺序为提取次数>提取时间>料液比,其最佳提取条件为A2B2C2,即8倍量的甲苯提取液提取4次,每次45 min.实验证明该提取工艺方法经济合理.Using L9 （ 3^4 ） orthogonal experimental design, the exrtaction conditions of quinine sulfate in Cinchona were optimized under the guidance of the content determination and the yield of allcaloid. The Influencing factors was that extracting times 〉 extracting time 〉 solid： liquid ratio. The optimum extracting condition was A2B2C2, that is, adding 8 times of solvent, ultrasonic extraction 45 min, extraction of a total of four times. The optimized process is stable and highly efficient.

关 键 词：金鸡纳 超声提取 总生物碱 正交试验 

分 类 号：R284.2[医药卫生—中药学]