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出 处:《中国微生态学杂志》2008年第3期262-263,共2页Chinese Journal of Microecology
基 金:杭州市医学重点专科项目(2006533Q12)
摘 要:目的了解人工肝支持系统(ALSS)留置静脉导管相关性感染(CR I)的临床、病原学特点,探讨护理措施。方法对行ALSS治疗的肝衰竭患者留置的静脉导管尖端和外周血进行细菌学培养及药物敏感试验,实施相应护理。结果61例CR I中共分离出64株病原菌,其中革兰阳性菌56株,革兰阴性菌2株,真菌6株。最常见的是凝固酶阴性葡萄球菌,该菌对万古霉素敏感率为100%。结论严格无菌操作,及时拔除感染导管是防治CR I的有效方法,临床应以预防为主,万古霉素是治疗CR I的首选药物。Objective To understand clinical and etiologic characteristics of venous angioaccess-related infection in artificial liver support system-treated patients and explore the measures of prevention, nursing and treatment. Methods Bacterial culture and drug sensitivity test were performed in cusp of catheters after being pulled out and the peripheral blood in liver failure patients. Corresponding nursing must be taken. Results 64 strains were isolated from 61 cases CRI including 56 Gram-positive strains, 2 Gram-negative strains and 6 fungi strains, respectively. The most frequent organism were staphylococcus epidermidis which had high sensitivity to vancomycin. Conclusions Nursing operation must be strict and completely sterile. The most effective measure is removing catheters in time, and vancomycin is the most optimal reagent for catheter-related infection (CRI).
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