注意缺陷多动障碍儿童抑制功能研究  

Response inhibition in children with attention deficit hyperactivity disorder

作　　者：杨斌让[1] 陈楚侨[2] 静进[3] 张芳蓉[1] 李建英[4] 杨思渊[5] 

机构地区：[1]深圳市儿童医院,广东深圳518026 [2]中国科学院心理研究所,北京100101 [3]中山大学公共卫生学院,广东广州510080 [4]中山大学附属第三医院,广东广州510630 [5]广州市儿童医院,广东广州510120

出　　处：《中国儿童保健杂志》2008年第3期300-303,共4页Chinese Journal of Child Health Care

摘　　要：【目的】探讨注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)儿童是否存在抑制功能缺陷。【方法】运用反应/不反应任务、停止信号任务、Stroop色-字任务对100名ADHD儿童和对照组儿童进行抑制功能测试,运用多变量方差分析进行统计。【结果】两组儿童在反应抑制功能上差异有显著性,单因素方差分析显示ADHD组儿童在反应/不反应任务的反应时变异、停止信号任务的停止信号反应时及正确反应的反应时变异、Stroop色-字测试的干扰分(反应时及错误分)明显高于对照组儿童。控制FIQ后方差多变量分析及协方差分析仍有统计学意义。【结论】ADHD儿童在反应抑制功能领域存在缺陷。[Objective] To determine whether or not children with attention deficit hyperactivity disorder（ADHD） perform worse than healthy control children in cognitive function domains of response inhibition. [Methods] One hundred children with ADHD and 100 healthy controls matched in age,gender,grade,handedness were conducted with neuropsychological tests concerning the domain of response inhibition（go/no-go,stop signal task,Stroop color-word test）.Then they were compared with healthy controls,using multivariate analysis of variance（MANOVA）. [Results] The omnibus MANOVA of the primary neuropsychological variables（go/no-go and Stroop color-word test） revealed a large group effect [F（5,176）=13.121,P〈0.001].The ANOVAs of each test showed that children with ADHD performed worse than healthy controls in go/no-go,stop signal task,Stroop color-word test.After controlling for full-scale IQ（FIQ）,the distinctions of MANOVA and analysis of covariance（ANCOVA） remained unchanged. [Conclusion] There are significant deficiencies in response inhibition in children with ADHD.

关 键 词：注意缺陷多动障碍 反应抑制 执行功能 

分 类 号：R179[医药卫生—妇幼卫生保健]