原料粒度对磷酸钙骨水泥性能的影响  

Effects of the Particle Size on Properties of a Calcium Phosphate Cement

作　　者：杨娟娟[1] 王秀鹏[1] 叶建东[1] 

机构地区：[1]华南理工大学特种功能材料教育部重点实验室

出　　处：《材料科学与工程学报》2008年第3期400-405,共6页Journal of Materials Science and Engineering

基　　金：广东省科技计划资助项目(2004A11304001);广州市科技计划资助项目(2005Z3-D2041)

摘　　要：以等质量的部分结晶磷酸钙(PCCP)和磷酸氢钙(DCPA)的混合物组成的磷酸钙骨水泥(CPC)粉体作为研究对象,采用单因素实验,研究了PCCP和DCPA粒度变化对骨水泥抗压强度、孔隙率、凝结时间、水化产物物相组成和结晶形貌的影响。结果发现:在0.4的液固比下,固定PCCP的粒度,减小DCPA的粒径,骨水泥的抗压强度呈先升高后减小的趋势,存在一最大值为34.6MPa;而PCCP的粒度变化对骨水泥性能的影响较大,随着PCCP粒径的减小,所需调和液的比例增到0.5,抗压强度也存在一最大值为19.7MPa。而孔隙率随这两种原料粒度变化的规律都与强度的变化规律相反,随原料粒径的减小,均存在一最小值。DCPA的粒度变化对骨水泥的凝结时间影响不大;而随PCCP颗粒粒径的减小,骨水泥的凝结时间变短。所生成的水化产物都为弱结晶的羟基磷灰石(HA),但当DCPA颗粒较粗时,固化体中有微量的DCPA残余;而当PCCP颗粒过细时,固化体中有较多的DCPA残余。Calcium phosphate cement （CPC） powder mixed by partially crystallized calcium phosphate （PCCP） and dicalcium phosphate anhydrous （DCPA） with a mass ratio of 1 ： 1 was studied in this work . The effects of the particle size of PCCP and DCPA on compressive strength, porosity, setting time, phase composition and microstructure of the hydrated products were studied. Results show that at the liquid to powder ratio of 0.4mL/g and at the same particle size distribution of PCCP, as the particle size of the DCPA decreases, the compressive strength increases at first and then decreases, and the maximum value is 34.6 MPa. The particle size of PCCP significantly influences the properties of CPC. As the particle size of PCCP decreases, the liquid needed for mixing increases tb 0. 5 mL/g, and the maximum value of compressive strength is 19.7 MPa. The variations of porosity of CPC with different particle size of the PCCP and DCPA are reverse to the variations of compressive strength, both of them have minimum values. The particle size of the DCPA does not obviously alter the setting time; the setting of the cement is accelerated as the particle size of PCCP decreases. The hydrated product is poorly crystallized hydroxyapatite （HA）,but when the particle size of DCPA is too big, there is little DCPA remnant in the final products. Also when the particle size of PCCP is mall, there is some DCPA remnant in the final products.

关 键 词：磷酸钙骨水泥 粒度 抗压强度 凝结时间 孔隙率 

分 类 号：R318.08[医药卫生—生物医学工程]