北京市城区1400例妇女腰椎骨量与年龄和绝经的关系  

Relative Contribution of Ageing and Menopause to the Changes of Lumbar Bone Density in 1 400 Beijing Women

作　　者：程国钧[1] 袁艺[1] 刘建立[1] 张忠兰[1] 

机构地区：[1]解放军总医院妇产科

出　　处：《中华妇产科杂志》1997年第9期532-534,共3页Chinese Journal of Obstetrics and Gynecology

摘　　要：目的：分析妇女的腰椎骨量变化规律，为防治骨质疏松症提供依据。方法：对１４００例２０～８５岁居住在北京市城区的妇女，采用双能Ｘ线骨密度测定仪（ＤＥＸＡ）测量第１～４腰椎的骨矿含量（ＢＭＣ）和骨密度（ＢＭＤ）。结果：（１）ＢＭＣ和ＢＭＤ在３０岁以前随年龄增长而增加，３０岁达高峰，５０岁以后显著下降。（２）绝经前妇女，ＢＭＣ和ＢＭＤ达峰值后不随年龄增长有显著下降，绝经后１０年内出现快速骨丢失，早绝经妇女的骨量较低（Ｐ＜０．０５）。（３）绝经后骨质疏松症患病率１７．４０％。结论：绝经后１０年内出现快速骨丢失，此期是防治骨质疏松症的关键时期。Objective: To study the pattern of bone mass changes of women's lumbar spine, and obtain evidence to guide the prevention of postmenopausal osteoporosis. Method: Bone mineral content (BMC) and bone mineral density (BMD) of lumbar 1￣4 in 1 400 Beijing women aged 20￣85, were measured by dual energy X ray absorptiometry. Results: (1) Both BMC and BMD increased after age 20, reached the peak at the age of 30, and decreased significantly after the age of 50; (2) There was no significant change of BMC and BMD after the age of 25 in premenopausal women. Bone loss accele rated in the first 10 years after menopause. Women who experienced menopause early had lower bone mass. (3) The prevalence of osteoporosis in 1 121 postmenopausal women was 17.40%. Conclusion: Significant bone mass loss of lumbar spine occurs during the first decade following menopause, which is the key period for preventing osteoporosis.

关 键 词：骨质疏松 绝经后 骨密度 PMO 北京 

分 类 号：R588[医药卫生—内分泌] R681[医药卫生—内科学]