阿奇霉素治疗小儿支原体肺炎疗效分析  

The clinical observation of azithromycin in treating children's mycoplasma pneumonia.

作　　者：陈静[1] 谢毅[1] 

机构地区：[1]成都市第六人民医院儿科,四川成都610051

出　　处：《四川医学》2008年第6期736-737,共2页Sichuan Medical Journal

摘　　要：目的观察阿奇霉素治疗小儿支原体肺炎疗效。方法治疗组阿奇霉素10mg/（kg·d）,静脉滴注,疗程3d,停4d,1周为1疗程。共1～2个疗程。对照组红霉素20～30mg/（kg·d）,静脉滴注,疗程7～14d。结果治疗组退热时间、咳嗽好转时间、音消失时间和平均住院时间均较对照组短,局部疼痛、胃肠道不良反应等明显低于对照组。差异有统计学意义（P〈0.05）。结论阿奇霉素治疗小儿支原体肺炎效果显著,疗程短,不良反应少,值得临床推广。Objective To evaluate the therapeutic effect of azithromycin on children＇s mycoplasma pneumonia. Methods 116 children with mycoplasma pneumonia were divided randomly into treatment group and control group. The treatment group were given a daily dose of 10mg/（ kg·d） of azithromycin administered by Ⅳ instillation for 3 days for every week. The course of treatment in both groups last 7 - 14 days. Results The pyretolysis time, cough improvement timerale disappearing time and mean length of hospitalization of treatment group were shorter than that of control group. The local ache, stomach and intestinal tract adverse reaction were less than those in control group. The difference was remarkable （ P 〈 0.05） . Conclusion Using azithromycin in children＇s mycoplasma can get better therapeutic effect and shorter period of treatment with less adverse reaction.

关 键 词：阿奇霉素 儿童 支原体 肺炎 

分 类 号：R725.6[医药卫生—儿科]