泛发性脓疱型银屑病35例临床分析  

Clinical analysis of 35 patients with generalized pustulosa psoriasis

作　　者：熊峰[1] 宋彪[1] 杜晓红[1] 梅忠喜[1] 

机构地区：[1]深圳市第一人民医院,广东深圳518020

出　　处：《中国热带医学》2008年第7期1143-1144,共2页China Tropical Medicine

摘　　要：目的分析GPP的临床特征及不同治疗方法的疗效。方法对35例住院GPP患者病例资料、临床特点和治疗经过进行回顾性分析。A)甲氨喋呤10～15mg静脉滴注每周1次;b)激素(用量相当于泼尼松量0.6～1.0mg/kg/d)+雷公藤多甙30～60mg/d;c)激素(同B)+泰尔丝30～40mg/d;d)激素(同B)+泰尔丝30～40mg/d+雷公藤30～60mg/d各种药物剂量随皮损变化逐步撤减。结果a、b、c和d疗法有效率分别为75%、80%、72%和89%。上呼吸道感染和药物是发病主要诱因。结论对于重症GPP应采用联合治疗方案。Objective To analyze the clinical features of generalized pustular psoriasis（GPP） and the efficiency of different treatments.Methods The 35 GPP cases were treated with four therapies：a）methotrexatum 10～15mg once per week;b）glucocorticoid 0.6～1.0mg/kg.d plus Leigongteng（a herbal drug） 30～60mg;c）isotretinoin capsules 30～40mg/d;d） glucocorticoid plus isotretinoin capsules plus Leigongteng 30～60mg/d.The results were analyzed.Results Upper respiratory infections and use of drugs were the main triggering factors.The effective rates of a,b,c and d were 75%,80%,72% and 89%.Conclusion Severe GPP should be treated with combination therapy.

关 键 词：脓疱型银屑病 治疗 疗效分析 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]