肺气肿片质量标准研究  

Study on quality standard of Feiqizhong Tablets

作　　者：位岩平[1] 王琦[2] 姜明章 冯景辉 

机构地区：[1]烟台市莱阳中心医院,山东莱阳265200 [2]中国人民大学信息学院,计算机科学技术05级北京100872 [3]烟台大洋制药有限公司,山东烟台265500

出　　处：《齐鲁药事》2008年第6期352-354,共3页qilu pharmaceutical affairs

摘　　要：目的建立肺气肿片的质量标准。方法采用薄层色谱法对肺气肿片中野马追、淫羊藿、补骨脂、黄芪和丹参进行定性鉴别；用高效液相色谱法测定肺气肿片中淫羊藿苷的含量。结果TLC鉴别方法准确，专属性强；淫羊藿苷在0．4464～2．2232μg范围内呈良好的线性关系（r=0．9997），平均回收率为100．3％，RSD=0．7％（n=5）。结论所建立的方法可靠、准确、专属性强，可有效控制肺气肿片的质量。OBJECTIVE To establish the quality standard for Feiqizhong Tablets. METHODS The Lindley eupatorium herb,Epimedium brevicornum maxim, Fructus psoraleae, Radix astragali and Radix salviae miltiorrhizae were identified by TLC. The content of icariin was determined by HPLC. RESULTS The spots in TLC were quite clear,the linear range of icariin was 0. 4464～ 2. 2232μg （ r = 0. 9997）, the average recovery was 100.3 % with RSD = 0. 7 % （ n =5）. CONCLUSION The method was reliable,specific and accurate,and can effectively control the quality of Feiqizhong Tablets.

关 键 词：质量标准 淫羊藿苷 肺气肿片 高效液相色谱 薄层色谱 

分 类 号：R927.11[医药卫生—药学]