Chemical constituents from the aerial parts of Plumbago zeylanica L.  

白花丹地上部分的化学成分(英文)

作　　者：黄小燕[1] 谭明雄[1] 吴强[1] 陈勇[1] 王恒山[1] 

机构地区：[1]广西师范大学化学化工学院药用资源化学与药物分子工程重点实验室,广西桂林541004

出　　处：《Journal of Chinese Pharmaceutical Sciences》2008年第2期144-147,共4页中国药学（英文版）

基　　金：973 Project(Grant No.2007CB516805);the Natural Science Foundation of Guangxi Province(Grant No.05112001-3B2);the Project of the Key Laboratory of Medicinal Chemical Resources and Molecular Engineering Guangxi Normal University(Grant No.0630006-5D09).

摘　　要：To investigate the chemical constituents from the aerial parts of Plumbago zeylanica L. The chemical constituents were isolated by various column chromatographic methods and the structures were elucidated by various spectroscopic methods, especially 2D- NMR spectra. A new tfiterpenoid, 1β,3β,1 1α-trihydroxy-urs-12-ene （1）, together with six known compounds, androsta-l,4-diene-3,17- dione （2）, isoshinznolone （3）, neoechinulin A （4）, harman （5）, ergostadiene-3β,5α,6β-triol （6） and N-（N＇-benzoyl-S-phenylalaninyl）-S- phenylalaninol （7） were isolated from the aerial parts ofP. zeylanica. Compound 1 was a new compound, and compounds 2, 4-7 were obtained from this genus for the first time.研究白花丹Plumbago zeylanica L.地上部分的化学成分。应用各种色谱方法分离;用波谱学方法特别是二维核磁共振波谱的方法确定结构。从白花丹地上部分分离鉴定了7个化合物,分别是:1β,3β,11α-trihydroxy-urs-12-ene(1),androsta-1,4- diene-3,17-dione(2),异信浓柿醇酮(3),neoechinulin A(4),barman(5),ergostadiene-3β,5α,6β-triol(6),N-(N-benzoyl-S-phenylalaninyl)- S-phenylalaninol(7)。化合物1为新化合物,化合物2,4-7均为首次从该属植物中分离得到。

关 键 词：Plumbago Plumbago zeylanica L. Chemical constituents 

分 类 号：R284.1[医药卫生—中药学]