电场对红细胞沉降率的影响Ⅵ──电场方式依赖性  

Effeet of Electric Field on Erythrocyte Sedimentation Rate Ⅵ ─Dependence of Electric Field Pattern

作　　者：谢玲玲[1] 龙勉[1] 刘延海[1] 王红兵[1] 宋关斌[1] 吴泽志[1] 吴云鹏[1] 

机构地区：[1]重庆大学生物工程研究院,重庆630044

出　　处：《生物医学工程学杂志》1997年第3期237-242,共6页Journal of Biomedical Engineering

基　　金：四川省青年科技基金

摘　　要：利用自行研制的红细胞流变参数自动测试分析仪及显微形态观测法，研究了三种电场方式对红细胞在生理盐水溶液中及在自体血浆中沉降及聚集特性的影响。结果表明，交流电场能使悬浮于生理盐水溶液中的红细胞产生轻度聚集，沉降过程加快。直流恒流电场不能使悬浮于生理盐水中的红细胞发生聚集，其沉降过程加快仅是电场力作用所致。直流恒压电场作用下红细胞在生理盐水溶液中的沉降曲线为指数形，但这种指数形曲线与红细胞聚集无关，而是回路中电流随时间下降所致。实验结果还显示上述电场方式均在不同程度上影响红细胞在自体血浆中的沉降过程，预示电场作用下红细胞在血浆中的聚集行为发生了变化。An automatic analyzer of RBC rheological parameters and a microscopic morphological observationtechnique were employed to investigate the effect of three electric field patterns on erythrocyte sedimentation andaggregation in a physiological saline solution and in autologous plasma,respectively. Experimental results indicatethat in a physiological saline solution: 1)Erythrocytes present a lightly aggregation and settle faster by an alternative current electric field ; 2)There exists no erythrocyte aggregation by a direct current electric field of constantcurrent and the enhancement of erythrocytgr sedimentation is caused only by the action of electric force j 3 )Timecourses of erythrocyte sedimentation fit well with an exPOnential type curve by a direct current electric field of constant voltage,and this exponential type sedimentation curve is not caused by erythrocyte aggregation but caused bythe decrease of circuit current with time duration. Also shown by experimental results is that the above three electric field patterns all affect the erythrocyte sedimentation in antologous plasma in different contents,which predictssome change in erythrocyte aggregation behavior in autologous plasma by an external electric field.

关 键 词：电场 红细胞 沉降 聚集 沉降率 依赖性 

分 类 号：R446.11[医药卫生—诊断学]