286例儿童流行性乙型脑炎的临床特征分析  

Clinical analysis of 286 cases of Japanese encephalitis(JE) in children

作　　者：何志慧[1] 蒋莉[1] 李听松[1] 

机构地区：[1]重庆医科大学附属儿童医院神经内科,400014

出　　处：《重庆医学》2008年第14期1572-1574,共3页Chongqing medicine

摘　　要：目的总结重庆地区儿童流行性乙型脑炎（乙脑）的临床特征，比较2005年与2006年患者的差异。方法收集2006年7～9月及2005年同期重庆医科大学附属儿童医院收治共286例乙脑患儿的临床资料，对其临床特征作回顾性分析。结果2年患儿皆符合乙脑的一般临床特征；与2005年组比较，2006年组疫情严重，表现为发病例数增加，起病急、发展快、病情重，并发心肌损害比率高；而且乙脑特异性IgM抗体检查阳性率较2005年组显著降低。结论每年流行性乙脑的临床特征不尽相同，可能与传染源、致病病毒株（存活能力、毒力、繁殖能力）、传播媒介等相关因素不尽相同有关。重庆地区2006年的高温酷暑天气和大旱，可能是导致这种差异性的气候、环境因素。Objective To investigate the clinical characteristics of Japanese encephalitis（JE） in the children of Chongqing district in 2005 and 2006,and to explore their difference. Methods The clinical data of 286 cases inflicted with JE admitted to Chidren＇s Hospital of Chongqing Medical University from July to September in 2006 was collected, and the retrospective analysis was pro- cessed between the data and that from the same period in 2005. Results The clinical characteristics of all the cases were accorded with diagnosis criteria of JE. Compared with the cases in 2005, the condition of patient was severer, total number of JE cases was much more, the illness was very acute and the development fast, the rate of complication of myocardial damage was higher and the detection rate of JE virus specific IgM was lower in 2006. Conclusion The clinical characteristic of JE at different time was not completely same, and this may due to the difference in the viability of infection source, pathogenesis virus（survival ability, toxicity, reproduction ability） and vector. High temperature and great drought in the summer in Chongqing district may be the possible causes for the variability of climate and environmental factor.

关 键 词：儿童 流行性乙型脑炎 临床特征 

分 类 号：R725.1[医药卫生—儿科]