【1-^(14)C】棕榈酸的合成  

Synthesis of 1 14 C palmitic acid

作　　者：田原[1] 韩佩珍[1] 田淑浩[1] 

机构地区：[1]中国医学科学院中国协和医科大学放射医学研究所

出　　处：《核技术》1997年第9期572-574,共3页Nuclear Techniques

摘　　要：报道了由［１４Ｃ］碳酸钡产生１４ＣＯ２、并通过格氏反应制备［１－１４Ｃ］棕榈酸的方法，其放射性收率为４４．８％。经高效液相色谱分析测得放射化学纯度＞９９．５％。经薄层层析检测确证产品为不含任何杂质的［１－１４Ｃ］棕榈酸纯品。The synthesis of[1 14 C]palmitic acid via Grignard Reaction is reported The carbon C 14 dioxide was liberated by dropping sulfuric acid onto barium carbonate C 14 The yield of [1 14 C] palmitic acid was 44 8% A radiochemical purity of more than 99 5% was determined by HPLC and the product was proved to be free of impurity by TLC

关 键 词：棕榈酸 格氏反应 合成 同位素标记药物 

分 类 号：TQ463.7[化学工程—制药化工]