微波辅助萃取牡荆挥发油的气相色谱-质谱分析  

Study on essential oils from vitex negundo L.var.cannabifolia (Sieb.et Zucc.) Hand.-Mazz by microwave method

作　　者：黄琼[1] 陈丽芬[1] 陈海燕[1] 黄克建[2] 钱志勇[3] 林翠梧[1] 

机构地区：[1]广西大学化学化工学院 [2]广西公安厅,广西南宁530012 [3]四川大学华西医院生物治疗国家重点实验室,四川成都610041

出　　处：《中国现代医学杂志》2008年第12期1715-1716,1721,共3页China Journal of Modern Medicine

基　　金：广西科技攻关项目(No:0480005);广西大学科学技术研究重点基金资助项目(No:2003ZD005)

摘　　要：目的提供一种新型提取牡荆挥发油的方法。方法采用微波辐射法提取牡荆的挥发油,运用毛细管气相色谱-质谱联用法结合计算机检索,对其化学成分分别进行分析和鉴定,用面积归一化法测定各化合物在挥发油中的相对含量。结果共鉴定出16个化合物,挥发油的主要成分为石竹烯(20.14%)、4-羟基-苯甲酸(21.16%)、桉叶油素(12.79%)。结论通过微波辅助萃取法可以高效提取牡荆挥发油。[Objective] To submit a new method to extract essential oils from Vitex negundo L.var.cannabifolia （Sieb.et Zucc.）Hand.-Mazz by microwave method. [Methods] The essential oils from Vitex negundo L.var.cannabifolia （Sieb.et Zucc.）Hand.-Mazz were extracted by microwave method, then the constituents were separated and identified by GC-MS, and their relative contents were determined by area normalization. [Results]16 compounds were identified, and the principal chemical constituents are caryophyllene （20.14%）, benzoic acid, 4-hydroxy-（21.12%）, eucalyptol （12.79%）. [Conclusion] It is a great method to extract essential oils in high yield from Vitex negundo L.var.cannabifolia（Sieb.et Zucc.）Hand.-Mazz by microwave method.

关 键 词：牡荆 微波法 挥发油 GC-MS 

分 类 号：R284.1[医药卫生—中药学]