超临界流体技术进行熔融肉豆蔻酸的微粉化  

Myristic Acid Micronization from Its Melt Using Supercritical Fluids

作　　者：洪玮[1] 陈辉[1] 王霞[1] 洪金堆[1] 苏玉忠[1] 王宏涛[1] 李军[1] 

机构地区：[1]厦门大学化学化工学院,福建厦门361005

出　　处：《厦门大学学报（自然科学版）》2008年第4期541-546,共6页Journal of Xiamen University：Natural Science

基　　金：福建省新世纪优秀人才支持计划;福建省自然科学基金(E0710026)资助

摘　　要：设计和搭建了一套能够进行熔融物制备固体微颗粒的实验装置，利用超临界CO2以及超临界N2制备肉豆蔻酸的超细微粒，研究预膨胀压力、预膨胀温度、喷嘴大小对颗粒大小以及粒径分布的影响．结果表明：在研究范围内，随着预膨胀压力（8～16MPa）的增加，肉豆蔻酸颗粒粒径变小和粒径分布变窄；随着预膨胀温度（50～70℃）的增加，肉豆蔻酸颗粒粒径变大和粒径分布变宽；喷嘴大小（60～120um）对肉豆蔻酸颗粒几乎没有影响；使用超临界CO2制备的肉豆蔻酸颗粒形貌为不规则形状，但颗粒可以方便地控制在0．5～2um内；使用超临界N2制备的肉豆蔻酸颗粒形貌为球状，颗粒可以控制在0．5～20um内．Supercritical fluid-assisted technology generation of micro- or nano- particles has attracted a growing interest for scientists in various fields. Among them,supercritical fluid/gas-saturated melts can be conveniently used for atomizing to form uniform and fine particles. Toward to the end, an apparatus was designed and established for generation of microparticles from melted myristic acid by using both supercritical CO2 and supercritical N2. The effects of the pre-expansion pressure, pre-expansion temperature and nozzle diameter on the morphology,size and size distribution of the produced myrisitc acid particles were investigated. In the pressure range of 8- 16 MPa,results showed that the particle size decreases and the particle size distribution narrows with increasing the pre-expansion pressure. Furthermore,the particle size increases and the particle size distribution broadens with increasing the pre-expansion temperature in the range of 50- 70℃. Results also showed that the nozzle diameter in the range of 60-120 microns had slight effect on the produced particles. In the context of particle morphology,irregular particles with a narrow size distribution in 0.5 - 2 microns were produced using supercritical CO2, while spherical microparticles within 0.5 - 15 microns were produced when using supercritical N2.

关 键 词：超临界CO2 超临界N2 肉豆蔻酸 微颗粒 

分 类 号：TQ028.8[化学工程] TQ029.1