病因分析和预防性治疗在复发性早期流产中的价值  

Etiology analysis and prophylactic treatment in the management of recurrent early abortion

作　　者：韩素云[1] 王珊珊[1] 袁鹏[1] 余良宽[1] 王欣[1] 黄国香[1] 李慧敏[1] 

机构地区：[1]兰州军区乌鲁木齐总医院妇产科,新疆乌鲁木齐830000

出　　处：《中国妇幼保健》2008年第10期1335-1337,共3页Maternal and Child Health Care of China

摘　　要：目的:分析复发性早期流产的病因,探讨预防性治疗在预防早期自然流产中的价值。方法:应用染色体分析、B超、内分泌检查及免疫学等方法对90例复发性早期流产的病人进行系统筛查,并进行有针对性的预防性治疗。结果:90例复发性早期流产患者夫妻外周血染色体核型均正常;63例患者有不同类型的内分泌异常,占70.0%;30例夫妇出现免疫学异常,占33.3%;9例患者出现不同类型的生殖道疾患,占10.0%;20例患者存在生殖道感染,占22.2%;13例患者丈夫精液异常,占14.4%;9例患者原因不明,占10.0%。经过预防性治疗,90例中63例正常分娩,6例中期妊娠,成功率为77.8%。结论:复发性早期流产病因是多因素混杂存在的,内分泌因素、免疫因素可能是导致复发性早期流产的主要因素,针对病因进行预防性治疗值得推荐。Objective： To study the etiology of recurrent early abortion and the value of prophylactic treatment in the management of these patients. Methods： Chromosome analysis, Bultrasound, endocrinology and immunology were used in the screen of the etiology. Then prophylactic treatment was applied respectively according to the causes. Results： Of all these 90 cases, 63 women showed different types of dyscrinism, 30 couples had immunological abnormality, 9 patients had gynecological problems, 20 patients were complicated with genital tract infections, 13 husbands were diagnesed as dysspermatism, 9 cases were idiopathic. The success ratio of prophylactic treatment was 77. 8%, of which 63 women delivered successfully, 6 women were in their midtrimester pregnancy. Conclusion： The etiology of recurrent early abortion is muhlfactorial and the causes of each patient may be complicating. Endocrinological and immunological disturbance are blamed to be the main possible culprits. Prophylactic treatment based on etiological analysis are recommended in the management of these patients.

关 键 词：复发性早期流产 病因学分析 预防性治疗 

分 类 号：R714.21[医药卫生—妇产科学]