邻苯二甲醛和强化戊二醛杀灭细菌芽孢效果比较  

Comparison the germicidal efficacy between ortho-phthalaldehyde and potentiated glutaraldehyde in disinfection of spores

作　　者：胡国庆[1] 徐燕[2] 潘协商[1] 陆烨[1] 

机构地区：[1]浙江省疾病预防控制中心,杭州310051 [2]江苏省疾病预防控制中心

出　　处：《中国公共卫生》2008年第7期800-801,共2页Chinese Journal of Public Health

摘　　要：目的比较邻苯二甲醛消毒剂与强化戊二醛消毒剂对枯草杆菌黑色变种芽孢的杀灭效果。方法采用载体定量杀菌试验对两者的杀灭效果和连续使用稳定性进行比较。结果0.53%邻苯二甲醛消毒液作用3 h对不锈钢片上枯草杆菌黑色变种芽孢的杀灭对数值为3.21,作用10 h杀灭对数值>6.10;而2.18%强化戊二醛消毒液作用3 h杀灭对数值>6.10;0.53%邻苯二甲醛消毒液连续使用7、14 d后,仍保持对芽孢有良好的杀灭能力。结论邻苯二甲醛消毒剂杀灭细菌芽孢的效果不如强化戊二醛,但可具备用于内镜高水平消毒效果和使用稳定性。Objective To compare the germicidal efficacy between ortho-phthalaldehyde and potentiated glutaraldehyde in disinfection of spores of Bacillus subtilis var. niger. Methods Carrier quantitative disinfection test was used to make comparison of the two disinfectants in their gerimicidal efficacy and constinuous stability. Results The logarithm value of disin- fection spores of Bacillus subtilis var. niger exposed to 0.53% ortho-phthalaldehyde for 3 h was 3.21 and that of 10 h was higher than 6.10. The same disinfection logarithm value of 2.18% potentiated glutaraldehyde for 3 h was higher than 6.10. In continuous stability test, the germicidal efficacy of 0.53 % ortho-phthalaldehyde in disinfection of the spores was effective after 7 and 14 days of contionous use. Conclusion At the same concentration, the sporicidal efficacy of ortho-phthalaldehyde was weaker than that of potentiated glutaraldehyde, but ortho-phthalaldehyde still is of high germicidal efficacy and comtinuous stabinty for endoscopes.

关 键 词：邻苯二甲醛 戊二醛 枯草杆菌黑色变种芽孢 

分 类 号：R927.11[医药卫生—药学] R446.112