用四丁基溴化铵相转移催化合成α-取代芳香乙腈  

Synthesis of α-substituted aryl acetonitriles catalyzed by phase transfer catalysis

作　　者：康君辉[1] 娜珍[1] 温伟江[1] 陈晓航[1] 余明新[1] 

机构地区：[1]浙江大学化学系,浙江杭州310027

出　　处：《化学试剂》2008年第7期497-499,共3页Chemical Reagents

基　　金：浙江省工业催化重中之重学科开放基金资助(56310108009)

摘　　要：芳香乙腈与卤代烃在50%NaOH溶液中经(Bu-t)4NBr相转移催化,合成了一系列α-取代芳香乙腈,产物结构通过IR1、HNMR、元素分析确证。这是一种无有机溶剂的绿色反应。Aryl acetonitriles can react with halohydrocarbon in a 50% NaOH solution to give a-substituted aryl acetonitriles under the PTC of （t-Bu）4NBr, and their structures were confirmed by IR, ^1HNMR, and EA. The synthetic method is organic solvent-free and belongs to a kind of green chemical reactions.

关 键 词：芳香乙腈 卤代烃 四丁基溴化铵 相转移催化(PIC) α-取代芳香乙腈 

分 类 号：O657[理学—分析化学]