米索前列醇舌下含服导致严重过敏反应  

Severe anaphylactic reaction induced by sublingual misoprostol administration

作　　者：任爱民[1] 姜秀娟[1] 白静[1] 

机构地区：[1]北京地坛医院妇产科,北京100011

出　　处：《药物不良反应杂志》2008年第3期214-215,共2页Adverse Drug Reactions Journal

摘　　要：1例30岁女性患者因产后出血,给予米索前列醇600μg舌下含服。15min后患者突然出现头晕、寒战、憋气、面色苍白、四肢厥冷、精神萎靡并出冷汗。查体示:BP150/100mmHg,P105次/min,R24次/min。考虑为米索前列醇过敏反应,立即给予吸氧,抗过敏治疗,并改用缩宫素治疗产后出血,7h后病情缓解。A 30-year-old woman with postpartum hemorrhage received sublingual misoprostol 600 μg. Fifteen minutes later, the patient suddenly developed dizziness, chill, breath holding, pale face, peripheral coldness, listlessness, and cold sweat. Physical examination showed a BP of 150/100 mmHg, P of 105 beats/min, R of 24 breaths/min. Misoprostol-induced anaphylactic reaction was suspected. The woman was given oxygen, anti-anaphylactic therapy immediately, and misoprostol was replaced with oxytocin for treating postpartum hemorrhage. Seven hours later, her symptoms were relieved.

关 键 词：米索前列醇 过敏反应 

分 类 号：R595.3[医药卫生—内科学]