心肌缺血早期ECT功能影像学特点分析  

Analysis the characteristic of early myocardial ischemia with functional tomoscintigraphy

作　　者：李小东[1] 宋昱[2] 赵洪刚[1] 张遵城[1] 董华[1] 董萍[1] 郭永涛[1] 张悦[1] 

机构地区：[1]天津医科大学第二医院核医学科,天津300211 [2]天津市泰达国际心血管医院

出　　处：《中国医师杂志》2008年第6期724-726,共3页Journal of Chinese Physician

摘　　要：目的揭示心肌缺血患者的心脏功能学变化特点，旨在提高早期诊断的准确性和敏感性。方法对39例无症状心肌缺血（SMI）、58例心肌缺血（AN）、46例阴性对照组和73例阳性对照组的陈旧心肌梗死（OMI）分别进行心肌灌注断层显像和门控心室功能ECT显像，各纽参数分析比较时，将年龄作为协变量进行协方差分析，然后进行SNK—Q检验和多重比较排序。结果AN组和SMI组呈现可逆性放射性缺损或分布减低，SMI异常病灶多为单发；除最大充盈时间（TPFR）外，各组的左室射血分数（EF）、峰值充盈速率（PFR）和峰值收缩速率（PER）均数间差异有统计学意义；PFR和PER值的排序如下：OMI组〈AN纽〈SMI组和对照组。结论SMI对心肌的损害和引起PFR和PER减低较AN纽轻微，对心脏舒缩功能无显著性影响，而且明显高于OMI组。Objective To observe the characteristic changes in cardiac function and to raise diagnostic accuracy and sensibility, Methods 39 silent myocardial ischemia and 58 angina and 46 age-matched healthy subjects and 62 obsolete myocardial infarction underwent myocardial tomography imaging and gated ventricular imaging. Covariance analysis was used to compare difference between SPECT imaging and parameters of function. The age was tested as covariate factor, then SNK-Q test and muhiple comparison were carried on. Results The silent myocardial ischemia and angina showed reversible radioactive defect or fixed defect, Most of myocardial SMI showed single peak exempt TPFR, EF, PFR and PER showed remarkably statistical difference （ P 〈0. 01 ）. The multiple comparison of PFR and PER was increased according by OMI, AN, SMI and negative control group （ P 〈 0. 05）. Conclusions The myocardial damage and PFR, PER in SMI is lower than that in AN group, which have no remarkably influence on the parameters of diastolic and retractile function in left ventricular.

关 键 词：心肌缺血 放射性核素显像 临床分析 治疗方法 

分 类 号：R816.2[医药卫生—放射医学]