人工肺的应用与肺膜材料性能评价  

Application of lung prosthesis and property of lung membrane materials

作　　者：古群英[1] 陈添华[2] 宋晓林[1] 高雪萍[1] 

机构地区：[1]井冈山大学附属医院,江西省吉安市343000 [2]井冈山大学医学院,江西省吉安市343000

出　　处：《中国组织工程研究与临床康复》2008年第23期4522-4524,共3页Journal of Clinical Rehabilitative Tissue Engineering Research

摘　　要：人工肺是在膜两侧进行气体、血液之间交换的场所,一般中空纤维是人工肺的主要部件。膜式人工肺是一种接近人体生理状态,较为理想的人工肺。它以人工合成的高分子材料制备的微孔膜作血液和气体的交换场所,完成人体的生理氧和过程,因而可暂时代替人体肺进行气体交换,用以支持生命以争取心、肺病变治愈及功能恢复的机会。膜式人工肺因选用的高分子材料、微孔膜的形式、血液和气体的流动方式的不同可有多种类型。但是至今还存在着未能解决的问题是与血液相接触的膜材料血液相容性仍不理想。本文从肺的功能出发,分析膜式人工肺的特点。Lung prosthesis is designed to exchange gas and blood on two sides of the lung membrane, mainly comprising hollow fiber. Membrane oxygenator is close to the human physiological conditions, and has been considered to be an ideal lung prosthesis. It is the microporous membrane, which are mainly prepared with artificial polymer materials, that can exchanges gas and blood, complete the process of human physiological oxygenation. Thus it can be used as temporary substitute of lung prosthesis to support the healing of cardiopulmonary disease and the restoration of function. Membrane oxygenator is varying due to the differences of polymer materials, microporous membrane and exchanging mode of blood and gas. However, the blood compatibility of membrane materials is unsatisfactory. The aim of this study is to analyze the membrane oxygenator and improve the blood compatibility of membrane oxygenator, as well as the development trend.

关 键 词：人工肺 中空纤维 膜材料 血液相容性 

分 类 号：R318[医药卫生—生物医学工程]