药物纤维及其在新型给药系统中的应用  

Iatric fiber and its application in novel drug delivery system

作　　者：余灯广[1] 申夏夏[1] Chris Branford-White 朱利民[1] 

机构地区：[1]东华大学生物科学与技术研究所,上海201620 [2]伦敦都市大学卫生研究与政策所

出　　处：《合成纤维工业》2008年第3期57-61,共5页China Synthetic Fiber Industry

基　　金：中英药用纺织品联合实验室和教育部生物医用纺织材料111项目(b07024)

摘　　要：综述了制备药物纤维的材料和技术以及药物纤维在新型给药系统(DDS)中的应用。分析了目前药物纤维DDS技术存在的问题。药物纤维可分为原料型、天然纤维的后整理型、聚合物型及复合型。其制备方法主要有传统纺丝方法、静电纺丝技术、非织造布技术以及后整理技术。指出中草药纤维的DDS、智能释药纤维DDS及多药多级控释DDS是今后药物纤维DDS研究的方向。The raw materials and technologies for iatric fiber were reviewed, as was the application of iatric fiber in novel drug delivery system（DDS）. The existing problem in DDS technology for iatric fiber was analyzed. The iatric fiber can be classified into raw material type, after-finishing type from natural fiber, polymer type and complex type. The production technologies included traditional spinning process, electrospinning process, non-woven process and after-finishing process. It was pointed out that the DDS development trend be focused on Chinese herb fiber DDS, intelligent releasing iatric fiber DDS and multi-drug multi-stage controlled releasing DDS.

关 键 词：药物纤维 给药系统 成纤聚合物 静电纺丝 药剂学 

分 类 号：R94[医药卫生—药剂学]