磺化羟乙基化交联壳聚糖对血清中低密度脂蛋白的吸附性能研究  

THE STUDIES OF ADSORPTION PROPERTIES OF SULFONATED HYDROXYETHYL CROSSLINKED CHITOSAN BEADS FOR LOW DENSITY LIPOPROTEIN IN PLASMA

作　　者：余艺华[1] 顾汉卿 何炳林[1] 郑治纲[2] 白铁环[2] 王宗泽[2] 

机构地区：[1]南开大学高分子化学研究所吸附分离功能高分子材料国家重点实验室 [2]天津南开医院检验科

出　　处：《高分子学报》1997年第5期606-610,共5页Acta Polymerica Sinica

基　　金：国家自然科学基金

摘　　要：磺化羟乙基化，交联壳聚糖，低密度脂蛋白，高密度脂蛋白，总蛋白。Using Sulfonated hydroxyethyl cross linked chitosan beads as adsorbents, adsorption experiments were performed by adding the beads to the plasma. The results showed that this type of adsorbent could cut down the concentration of LDL in plasma by 79.7% at most, while concentration of high density lipoprotein (HDL) and total protein (TP) decreased only by 7.3% and 2.6% at least respectively, so this type of adsorbent can be used to cure hyperlipidaemia in the future.

关 键 词：高脂血症 LDL 吸附剂 磺化羟乙基化 交联壳聚糖 

分 类 号：R318.08[医药卫生—生物医学工程] R589.205[医药卫生—基础医学]