促排卵中多卵泡发育者行IVF-ET或成熟卵泡刺破+宫腔内人工授精(IUI)的初步探讨  

Preliminary Discussion of Patients of Multi-follicle Development during Induced Ovulation Altered to IVF-ET or Mature Follicle Puncture +IUI

作　　者：李昆明[1] 滕晓明[1] 陈慧芬[1] 杨帆[1] 陈智勤[1] 杨健之[1] 朱丽萍[1] 王羽[1] 潘家坪[1] 邵敬於[1] 

机构地区：[1]同济大学附属第一妇婴保健院生殖医学中心,上海200040

出　　处：《生殖与避孕》2008年第6期375-378,共4页Reproduction and Contraception

基　　金：上海市卫生局青年课题资助项目;项目编号054Y09

摘　　要：目的:探讨促排卵治疗中多卵泡发育者的处理方法。方法:对于克罗米酚(CC)或hMG促排卵中发生多卵泡发育的30例患者,分别随机采用IVF-ET(A组)或成熟卵泡刺破+多余卵泡抽吸+宫腔内人工授精(IUI)(B组)的方法进行处理。结果:A组取卵周期妊娠率为26.67%,移植周期妊娠率为36.36%,与本中心同期同年龄段行IVF-ET者相比无统计学差异;B组妊娠率为13.33%,皆为单胎妊娠;二组所有患者均未发生OHSS。结论:促排卵治疗中出现多卵泡发育时,行IVF-ET或成熟卵泡刺破+多余卵泡抽吸+IUI是积极、有效、安全的治疗方法。Objective： To study the therapy methods of multi-follicle development during induced ovulation. Methods： IVF-ET or mature follicle puncture ＋ unnecessary follicles aspiration ＋ IUI was taken to treat patients of multi-follicle development during induced ovulation. Results： The pregnancy rate of OPU period, pregnancy rate of ET period of IVF group were 26.67%, 36.36%, respectively; no statistic differences were observed compared with those receiving regular IVF-ET in the same age group at the same time; the pregnancy rate of mature follicle puncture ＋unnecessary follicles aspiration ＋IUI group was 13.33%, no OHSS occurred in the two groups. Conclusion： IVF-ET or mature follicle puncture ＋unnecessary follicles aspiration ＋ IUI was effective and energetic for multi-follicle development during induced ovulation.

关 键 词：多卵泡发育 体外受精-胚胎移植(IVF-ET) 卵母细胞体外成熟培养(IVM) 卵泡刺破 宫腔内授精(IUI) 

分 类 号：R714.8[医药卫生—妇产科学]