细胞因子与Graves病的关系  

Relationship between cytokines and Graves' disease

作　　者：孟凤苓[1] 苏胜偶[1] 周红[1] 吴文成[1] 黄振国[1] 刘品力[1] 

机构地区：[1]河北医科大学第二医院内分泌科,石家庄050000

出　　处：《中华内分泌代谢杂志》2007年第6期517-518,共2页Chinese Journal of Endocrinology and Metabolism

摘　　要：检测Graves病患者甲巯咪唑治疗前后血清细胞因子水平,发现其血清可溶性白细胞介素2受体(sIL-2R)水平治疗前与正常对照组相比显著升高,治疗后恢复正常;血清白细胞介素8(IL-8)水平下降,治疗后无明显变化,与其它指标未显示相关性。GD患者IL-1β、IL-6、肿瘤坏死因子α水平与正常对照组无差异。Serum cytokine concentrations were determined in patients with Graves＇ disease （GD） before and after treatment of thiamazole. Serum soluble interleukin-2 receptor （sIL-2R） level was markedly raised before treatment as compared with normal subjects and returned to normal after 3 month therapy. Serum IL-8 level was lowered in GD patients and showed no change after 3 month therapy. No relationship between IL-8 and other markers was found. Serum IL-1β, IL-6 and TNF-α levels in GD patients showed no difference with those in normal controls.

关 键 词：格雷夫斯病 细胞因子类 免疫 

分 类 号：R581.1[医药卫生—内分泌]