颈动脉内膜硬化对冠状动脉病变的影响  

Relationship between Coronary Artery Disease and the Carotid Arteriosclerosis

作　　者：西雁[1] 张峰[1] 葛均波[1] 

机构地区：[1]复旦大学附属中山医院心内科,上海200032

出　　处：《中国临床医学》2008年第3期301-302,共2页Chinese Journal of Clinical Medicine

摘　　要：目的:探讨冠心病患者冠状动脉(冠脉)病变程度与颈动脉内膜中层厚度(IMT)和斑块积分的相关性。方法:选择行冠脉造影的胸痛患者56例(男性46例,女性10例),平均年龄71±9岁,根据冠脉造影结果分为无冠脉病变组、单支冠脉病变组、多支冠脉病变组。对所有入选患者行颈动脉彩超检查,测定颈动脉IMT值和斑块积分。结果:无冠脉病变组和单支冠脉病变组的颈总动脉IMT值均显著低于多支冠脉病变组(分别为0.77±0.24和0.92±0.25比1.24±0.55,均P<0.05),3组的颈动脉平均斑块积分(分别为0.3、1.4和2.5)随冠脉病变血管支数的增加而增加。结论:彩色多普勒超声检查观察颈动脉硬化程度可初步预测冠脉的病变情况。Objective：To investigate the relationship between the arteriosclerotic severity in coronary artery and that in common carotid artery.Methods：Coronary angiography and carotid ultrasound evaluation were performed in 56 patients.The intima-media thickness（IMT） and arteriosclerotic plaques in carotid arteries were evaluated with B-mode ultrasonography in all subjects.Results：The common carotid artery IMT in patients without coronary disease or with single vessel disease was significantly lower than that in patients with multiple coronary vessel disease（0.77±0.24,0.92±0.25 vs.1.24±0.55,both P〈 0.05）.A strong correlation between carotid artery plaque scores and coronary arteriosclerotic severity was found（P all 〈 0.05）.Conclusion：Ultrasonography of carotid artery could be used as a potential method for evaluating coronary arteriosclerotic severity.

关 键 词：内膜中层厚度 斑块积分 冠心病 

分 类 号：R541.4[医药卫生—心血管疾病]