三种药物流产服药方法的疗效观察  

Curative Effect Observation of Three Methods of Mifepristone Cooperating with Misoprostol on Drug Abortion

作　　者：胡静[1] 李小玲[1] 

机构地区：[1]西安市中心医院,陕西西安710003

出　　处：《实用医技杂志》2008年第22期2882-2884,共3页Journal of Practical Medical Techniques

摘　　要：目的:探索米非司酮配伍米索前列醇药物流产的服药方法,缩短用药时间,减少副反应。方法:将976例自愿药物流产的早孕妇女随机分为三组:150mg米非司酮分为A组(2日)、B组(3日)、C组(4日)服完,随后晨空腹来院服用米索前列醇600μg,观察流产率、孕囊排出时间、阴道出血时间、转经时间、不良反应情况等。结果:三组完全流产率、孕囊排出时间、出血时间及月经复潮时间差异无显著性;A组妊娠小于6周者完全流产率与妊娠6周～8周者相比差异有显著性;疗程短者出现副反应小,三组差异均有显著性。结论:米非司酮服用时间越短,其胃肠反应与头晕乏力等副作用越小;A组具有用时短、疗效确切、副作用小等优点,尤其对孕周小于6周患者流产效果好。Objective To investigate the taking medicine methods of mifepristone cooperating with misoprostol on drug abortion,to shorten the time of taking medicine,and to reduce the adverse reactions.Methods 976 cases of early pregnant women were divided into three group：150 mg overdosed by different time： A group （2 day）, B group （3 days）, C group（4 days）,then given 600 μg misoprostol on an empty stomach. And abortion rate,ettlux time of gestation sac,time of colporrhagia and returning menstruation, adverse reactions were examined.Results The abortion rate,ettlux time of gestation sac,time of colporrhagia and returning menstruation in three groups didn＇t have significant difference.But adverse reactions in them were shown significant difference.The complete abortion rate of pregnancy women less than 6 weeks was higher than that of 6 -8 weeks.Conclusion Shorter course of treatment,minor response were shown.Group A possesses advantages of short time,exact effect and little side effect,especially in less than 6 weeks duration of pregnancy.

关 键 词：米非司酮 米索前列醇 服药方法 药物流产 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]