特发性肺纤维化合并肺部感染32例临床分析  

Analysis of 32 Cases with Idiopathic Pulmonary Fibrosis Complicated Pulmonary Infection

作　　者：余更生[1] 蒋萍[1] 陶家驹[1] 

机构地区：[1]天津市第一中心医院呼吸科,天津市300192

出　　处：《中国全科医学》2008年第13期1144-1146,共3页Chinese General Practice

摘　　要：目的探讨特发性肺纤维化(IPF)合并肺部感染时抗菌药物的选择及治疗对策。方法对我院32例IPF合并肺部感染的患者的临床资料进行回顾性分析。结果共检出病原体52株,革兰阴性菌31株(为59.7%),其中9株对三代头孢等抗菌药物耐药;真菌9株(为17.2%)。大多数IPF合并肺部感染患者经抗菌治疗后肺部感染得到控制,93.0%的患者的病原体得以清除,3例死亡。结论IPF合并肺部感染的病原体多为革兰阴性菌,多需三代头孢加酶抑制剂的复合制剂及碳青霉烯类等药物来治疗,以期延缓病情和延长生存期。Objective To search the antibiotics use and treatment methods of IPF complicated with pulmonary infection. Methods Clinical data were retrospectively analyzed in 32 patients who suffered from IPF complicated with pulmonary in-fection. Results The total number of the pathogens was 52 strains, 31 strains were gram-negative bacilli （59.7%） , 9 strains were fungus （ 17.2% ） , The majority has better prognosis. 93.0% pathogen were clearanced, 3 death cases. Conclusion Most pathogen were gram-negative bacilli, Most of the patients were treated with a third-generation cephalosporin and carbapenems. Check the progress of disease and prolong survival time.

关 键 词：肺纤维化 肺部感染 抗菌药 

分 类 号：R563[医药卫生—呼吸系统]